The answer: YES. There are inputs for video and sound in the car, and there’s even an electrical outlet in the second row.
The only thing to watch out for would be flying controllers and nunchucks. My recommendation would be, as always, to make sure that you have everyone using a Wiimote to have the strap on. And make sure there’s enough distance between them and the next person so they don’t get socked when the player is trying to throw a pass etc.